How much does Selpercatinib cost?

Selpercatinib is a drug used to treat cancer in people whose tumors have changes (mutations or fusions) in specific genes (RET stands for "rearrangement during transfection"). It is usually given orally. Selpatinib is aRET receptor tyrosine kinase inhibitor indicated for the treatment of RET-driven non-small cell lung cancer, medullary thyroid carcinoma and thyroid cancer in appropriate patient populations.

Serpatinib, a kinase inhibitor, blocks an enzyme (kinase) and helps prevent cancer cell growth. Patients must undergo laboratory testing to confirm changes in the RET gene before starting treatment. The most common side effects include laboratory test changes (including increased liver enzymes, increased blood sugar, decreased white blood cell and platelet counts, decreased protein levels, decreased calcium, increased total cholesterol, increased creatinine, and decreased sodium), dry mouth, diarrhea, hypertension, fatigue, edema, rash, and constipation.

The original drug Serpatinib has not yet been launched in China, so it is not covered by medical insurance. Domestic patients cannot yet purchase this drug. Serpatinib marketed overseas The original drug has a US version and a European version. The price of the US version is about 150,000 yuan per box of 80mg*60 pills. The price of the European version of 80mg*56 pills per box is about 21,000 yuan (the price may fluctuate due to the exchange rate), which is expensive. There are also serpatinibgeneric drugs produced abroad. The specification produced by a Bangladesh pharmaceutical factory is 40mg*30 pills per box and the price is about 4,300 yuan (the price may fluctuate due to the exchange rate). The ingredients of the generic drugs are basically the same as those of the original drug.