Side effects of dolutegravir/lamivudine/tenofovir (Viropil, DTG/3TC/TDF)

Dolutegravir/Lamivudine/Tenofovir (Viropil, Viropil,DTG/3TC/TDF) is a combination drug used to treat human immunodeficiency virus (HIV) infection. Although this drug can effectively inhibit viral replication, it may also cause some side effects. Below is a list of possible side effects. Please note that different patients may respond differently and some side effects may be more common and others less common. If you experience any discomfort during use, please contact your doctor immediately for appropriate advice and treatment.

1.Gastrointestinal side effects: This is a common type of side effect and may include nausea, vomiting, diarrhea, abdominal discomfort, or heartburn. These discomforts may be noticeable when you first start taking the medication, but usually lessen over time. It is recommended to take the medication after meals to reduce gastrointestinal discomfort.

2.Headache: Some patients may experience mild headache while taking this medication, which is usually temporary.

3.Fatigue: Some patients may experience fatigue or weakness, which may affect daily activities. Proper rest and management can help relieve this symptom.

4.Abnormal liver function: In rare cases, use of dolutegravir/lamivudine/tenofovir may cause abnormal liver function. It is important to check your liver function regularly and follow your doctor's advice.

5.Abnormal renal function: Long-term use of nucleoside analog reverse transcriptase inhibitors (such as lamivudine and tenofovir) may affect renal function. Regularly checking kidney function and following your doctor's recommendations can help identify and manage potential problems early.

6.Bone health issues: Ingredients in tenofovir may be related to bone health. Long-term use may increase the risk of fractures and loss of bone density. Patients may need a bone density test and, if necessary, steps to protect bone health.

7.Lactic acidosis: Although rare, use of dolutegravir/lamivudine/tenofovir may cause lactic acidosis, a serious metabolic disorder. Patients should pay close attention to signs such as difficulty breathing, muscle pain, nausea, etc., and seek medical attention immediately if these symptoms occur.

8.Allergic reaction: Individual patients may be allergic to the ingredients in the drug and experience symptoms such as skin itching, urticaria, and facial edema. If an allergic reaction occurs, stop taking the medication and seek medical advice immediately.

9.Others: There are some other rare side effects, such as pancreatitis, muscle pain, neurological symptoms, etc. If these symptoms occur, seek medical attention immediately.

The above only lists possible side effects, and the actual situation may vary due to individual differences. Before using dolutegravir/lamivudine/tenofovir, be sure to read the drug instructions in detail, consult a professional doctor or pharmacist, and follow up regularly to monitor the drug's efficacy and side effects. Do not stop taking the medicine or adjust the dosage on your own, as this may affect the treatment effect and your health.

Dolutegravir/Lamivudine/Tenofovir (Viropil, Viropil, DTG/3TC/TDF) is not currently available in the country, so it cannot be purchased domestically and needs to be purchased through foreign channels. The cheaper ones abroad are Indian generic drugs, which cost about 450 yuan.