Dolutegravir/lamivudine/tenofovir (Viropil, DTG/3TC/TDF) warnings and precautions

Dolutegravir/Lamivudine/Tenofovir (Viropil, Viropil,DTG/3TC/TDF) is a combination drug used to treat human immunodeficiency virus (HIV) infection. While this drug is effective at inhibiting viral replication, there are some important warnings and precautions when using it. Here's what you need to know to ensure safe use of medications and minimize potential risks.

1. Only for the treatment ofHIV: Dolutegravir/Lamivudine/Tenofovir is only suitable for the treatment ofHIV infection and not for other viral infections or diseases. Do not use medicines for other than intended purposes.

2. Drug allergies and adverse reactions: Individual patients may be allergic to ingredients in the drug, and may experience symptoms such as skin itching, urticaria, and facial edema. If any allergic reaction or other adverse reaction occurs, stop taking the medication and seek medical advice immediately.

3. Liver function monitoring: While taking dolutegravir/lamivudine/tenofovir, your doctor may check your liver function regularly. If signs of liver function abnormalities occur, medication dosage adjustments or other measures may need to be taken.

4. Renal function monitoring: Long-term use of nucleoside analog reverse transcriptase inhibitors (such as lamivudine and tenofovir) may affect renal function. Check kidney function regularly and take appropriate measures according to your doctor's advice.

5. Bone health issues: The ingredients in tenofovir may be related to bone health, and long-term use may increase the risk of fractures and loss of bone density. Your doctor may recommend a bone density test and bone health protective measures as needed.

6. Lactic acidosis: Although rare, dolutegravir is used/Lamivudine/Tenofovir may cause lactic acidosis, a serious metabolic disorder. If symptoms of lactic acidosis such as difficulty breathing, muscle pain, and nausea occur, seek medical attention immediately.

7. Drug Interactions: Before using dolutegravir/lamivudine/tenofovir, be sure to tell your doctor about all the drugs you are using, including prescription drugs, over-the-counter drugs, and supplements. Certain drugs may affect how dolutegravir/lamivudine/tenofovir works or increase the risk of side effects.

8. Children, pregnant and lactating women: Dolutegravir/Lamivudine/The use of tenofovir in children, pregnant and lactating women may require special attention. Use in these populations should be under physician supervision to ensure safety and efficacy.

9. Necessary examinations and follow-up: While using dolutegravir/lamivudine/tenofovir, it is very important to have regular follow-up with your doctor. This includes regular monitoring of viral load, CD4 cell count, liver function, kidney function and other indicators to ensure that the efficacy and side effects of the drug are appropriately monitored.

10. Medication continuity: Please follow your doctor’s advice to take the medication on time, and do not stop the medication or adjust the dose at will. It may take some time for the effects of the medication to appear, so be patient and stick with it.

Finally, it is important to understand and follow your doctor's recommendations regarding the use of dolutegravir/lamivudine/tenofovir. If you have any concerns, discomforts, or questions, please feel free to speak with your doctor or professional healthcare provider. Do not change the medication method, dosage or stop medication on your own to avoid affecting the efficacy and health.

Dolutegravir/Lamivudine/Tenofovir (Viropil, Viropil, DTG/3TC/TDF) is not currently available in the country, so it cannot be purchased domestically and needs to be purchased through foreign channels. The cheaper ones abroad are Indian generic drugs, which cost about 450 yuan.