The price of dolutegravir/lamivudine/tenofovir (Viropil, DTG/3TC/TDF), how much does it cost per box?

Dolutegravir/Lamivudine/Tenofovir, also known as Viropril (brand name: Viropil), is a combination drug used to treat human immunodeficiency virus (HIV) infection. This drug achieves its therapeutic purpose by combining three different drugs, each with a different mechanism of action, to help inhibit viral replication and control HIV infection.

Dolutegravir/Lamivudine/Tenofovir (Viropil, Viropil, DTG/3TC/TDF) is not currently available in the country, so it cannot be purchased domestically and needs to be purchased through foreign channels. The cheaper ones abroad are Indian generic drugs, which cost about 450 yuan.

The three ingredients in this medication include:

1.Dolutegravir (Dolutegravir, DTG): Dolutegravir belongs to the category of integrase chain terminators. By blocking the activity of HIV integrase, it prevents the virus from integrating its genetic material into the DNA of the host cell, thus inhibiting the replication of the virus.

2.Lamivudine (Lamivudine, 3TC): Lamivudine is a nucleoside analog reverse transcriptase inhibitor that interferes with The reverse transcription process of HIV inhibits the virus from transcribing its RNA into DNA, thereby reducing virus replication.

3.Tenofovir (Tenofovir Disoproxil Fumarate, TDF): Tenofovir is also a nucleoside analog reverse transcriptase inhibitor. Similar to lamivudine, it can prevent the reverse transcription process of the virus and thereby reduce the replication of HIV.

Dolutegravir/Lamivudine/The combination of tenofovir acts on multiple key links of the HIV virus at the same time to achieve a more effective inhibition of viral replication. It can reduce viral load, maintain the patient's immune system function, reduce and delay disease progression, thereby improving the patient's quality of life. However, like other drugs, it may cause some side effects and needs to be used under the guidance of a doctor.