How much does a box of Riluzole cost?

Riluzole (Riluzole) is a glutamate antagonist (receptor, glutamate) used as an anticonvulsant (anticonvulsant) and prolongs survival in patients with amyotrophic lateral sclerosis (ALS), a disease that may also be called Lou Gehrig's disease. Riluzole is well absorbed (approximately 90%), with an average absolute oral bioavailability of approximately 60%. High-fat meals will reduce absorption, reducing AUC by approximately 20% and peak plasma concentration by approximately 45%.

Riluzole is metabolized primarily by the liver, including cytochromeP450-dependent hydroxylation and glucuronidation. CYP1A2 is the major isoenzyme involved in N-hydroxylation; CYP2D6, CYP2C19, CYP3A4 and CYP2E1 are considered unlikely to have a significant impact on riluzole metabolism in humans. Symptoms of overdose include neurological and psychiatric symptoms, acute toxic encephalopathy with coma, coma, and methemoglobinemia, which may be rapidly reversed if the patient is adversely affected by methylene blue therapy.

The original drug Riluzole has been launched in China and has entered the scope of Class B medical insurance. Specifications The price of 50mg*56 tablets per box may be around 4,000 RMB. The price of the Turkish version of Riluzole’s original drug, 50mg*56 tablets, sold overseas may be around RMB 1,200 per box (the price may fluctuate due to exchange rates). There are also generic drugs produced in other countries. The price of a box of 50mg*30 tablets produced by an Indian pharmaceutical factory may be around RMB 1,300 (the price may fluctuate due to the exchange rate). The pharmaceutical ingredients of generic drugs are basically the same as those of domestic and foreign original drugs. For specific prices and drug information, please consult Yaode Medical Consultants.