What are the side effects of Riluzole?

In placebo-controlled clinical trials (Studies 1 and 2) in patients with amyotrophic lateral sclerosis (ALS), a total of 313 patients were treated with Riluzole 50 mg twice daily. The most common adverse reactions that occurred in at least 5% of patients were fatigue, nausea, dizziness, decreased lung function, and abdominal pain. The most common adverse reactions that led to discontinuation of riluzole were nausea, abdominal pain, constipation, and increased alanine aminotransferase (ALT).

There was no difference in the incidence of adverse reactions leading to discontinuation in women and men. However, the incidence of dizziness is higher in women (11%) than in men (4%), adverse reactions are similar in older and younger patients, and there are insufficient data to determine whether adverse reactions differ by race. Adverse reactions caused by some cases of riluzole after its marketing include acute hepatitis and jaundice-type toxic hepatitis, renal tubular damage, and pancreatitis.

The original drug Riluzole has been launched in China and has entered the scope of Class B medical insurance. Specifications The price of 50mg*56 tablets per box may be around 4,000 RMB. The price of the Turkish version of Riluzole’s original drug, 50mg*56 tablets, sold overseas may be around RMB 1,200 per box (the price may fluctuate due to exchange rates). There are also generic drugs produced in other countries. The price of a box of 50mg*30 tablets produced by an Indian pharmaceutical factory may be around RMB 1,300 (the price may fluctuate due to the exchange rate). The pharmaceutical ingredients of generic drugs are basically the same as those of domestic and foreign original drugs. For specific prices and drug information, please consult Yaode Medical Consultants.