The effects and efficacy of Riluzole

Riluzole (Riluzole) is used in patients with amyotrophic lateral sclerosis (ALS), a motor neuron disease in which the nerve cells responsible for sending instructions to muscles gradually degenerate, leading to weakness, muscle atrophy and paralysis. Riluzole is used to prolong a patient's life or delay the need for mechanical ventilation. Riluzole should not be used in patients with any other form of motor neuron disease.

Patients in three studies were given 50, 100, or 200 mg of riluzole daily for up to 18 months. The mean survival time of patients who received riluzole was significantly longer compared with those who received placebo. Combining the results from the three studies, over 18 months, patients who took 100 mg of riluzole daily lived an average of 2 months longer than those who took a placebo. Riluzole 50 mg/day was no more effective than placebo, and 200 mg/day was no more effective than 100 mg/day, but the drug was no more effective than placebo in late-stage ALS.

The original drug Riluzole has been launched in China and has entered the scope of Class B medical insurance. Specifications The price of 50mg*56 tablets per box may be around 4,000 RMB. The price of the Turkish version of Riluzole’s original drug, 50mg*56 tablets, sold overseas may be around RMB 1,200 per box (the price may fluctuate due to exchange rates). There are also generic drugs produced in other countries. The price of a box of 50mg*30 tablets produced by an Indian pharmaceutical factory may be around RMB 1,300 (the price may fluctuate due to the exchange rate). The pharmaceutical ingredients of generic drugs are basically the same as those of domestic and foreign original drugs. For specific prices and drug information, please consult Yaode Medical Consultants.