What are the side effects of Besponsa?

Olintuzumab/Olintuzumab (Besponsa) is a drug used to treat acute lymphoblastic leukemia (Acute Lymphoblastic Leukemia, ALL). While it can help reduce the number of leukemia cells, it can also cause some adverse effects. The following are some possible side effects of oxinutuzumab/oxinutuzumab:

1.Fever: Fever is one of the common adverse reactions during oxinutuzumab/oxinutuzumab treatment. Patients may develop high fever, which usually needs to be managed under medical supervision.

2.Infection: Because oxinuximab/oxinuximab affects the function of the immune system, patients are more susceptible to infections. This includes an increased risk of bacterial, viral and fungal infections.

3. Anemia can cause symptoms such as fatigue, weakness, and dizziness.

4.Bleeding tendency: This drug may affect the function of platelets, increasing the risk of bleeding and congestion. Patients may be prone to bruises, nosebleeds, or wounds that are prone to bruises.

5.Nausea and vomiting: Nausea and vomiting are common discomforts during oxinutuzumab/oxinutuzumab treatment. These symptoms may require medication to reduce.

6.Liver function abnormalities: Some patients may develop liver function abnormalities during treatment, including elevated liver enzyme levels. This needs to be monitored and managed.

7.Headache: Patients may experience headaches or other neurological symptoms during treatment with oxinuximab/oxinuximab.

8.Gastrointestinal discomfort: In addition to nausea and vomiting, some patients may experience gastrointestinal discomfort such as diarrhea, abdominal pain, or indigestion.

9.Skin Reactions: Oxantozumab/Oxantozumab may cause skin reactions, such as rash or itching. These symptoms usually require a doctor's attention.

10.Neurological symptoms: Some patients may experience neurological symptoms during treatment, including dizziness, insomnia, anxiety, etc.

11.Immune-related adverse reactions: Similar to other targeted immunotherapy drugs, Ocelotuzumab/Olintuzumab may cause immune-related adverse reactions, such as cytolysis syndrome (Cytokine Release Syndrome,CRS) and neurotoxicity.

It should be emphasized that each patient's response to oxinutuzumab/oxinutuzumab may be different, and different doses and treatment regimens may lead to different side effects. TreatmentALLusually requires close supervision and individualized management by a physician to ensure patients receive optimal results and reduce the risk of adverse reactions during treatment. Communication between patients and doctors is very important, and patients should always report any new symptoms or discomfort to their doctors for timely intervention and management.

Oplusintuzumab/OlintuzumabIt has been launched in China, but it is not included in medical insurance. The domestic price is around 60,000 to 70,000 yuan, which is very expensive. Patients can buy it domestically. There are only original drugs available abroad, mainly Pfizer’s original drugs, which cost more than 80,000 yuan.