What kind of medicine is Nintedanib?

Nintedanib(Nintedanib) belongs to the tyrosine kinase inhibitor class of drugs and is used to treat idiopathic pulmonary fibrosis. It helps prevent changes in lung tissue. It is also used to treat chronic (long-term) interstitial lung disease, in which pulmonary fibrosis continues to develop or worsen. This drug is also used to slow the decline in lung function in people with interstitial lung disease associated with systemic sclerosis.

Nintedanib, a tyrosine kinase inhibitor, blocks an enzyme called tyrosine kinase in cells in the lungs. Blocking these enzymes helps reduce the formation of fibrous tissue in the lungs, thereby preventing symptoms of lung disease from worsening. This medicine comes in capsules, and the usual recommended dose is 150mg capsules, swallowed with liquid, twice a day, about 12 hours apart, with food. If a patient experiences side effects or changes in liver tests after taking it, the dose may be reduced or treatment may be suspended under the guidance of a doctor.

The original drug of nintedanib is marketed in China as nintedanib ethanesulfonate soft capsules and is covered by Class B medical insurance, but reimbursement is limited to patients who meet the indications. SpecificationsThe price of each box of 150mg*30 capsules may be more than 4,000 yuan. Nintedanib Original drug available overseas has Turkish version and Indian version, specificationsThe price of 150mg*60 capsules per box may be more than 5,000 RMB (the price may fluctuate due to the exchange rate). There are also nintedanib generic drugs produced overseas in other countries. For example, the price of 150mg*30 capsules produced by BDR Pharmaceutical Factory in India may be several hundred yuan per box (the price may fluctuate due to exchange rates). Its pharmaceutical ingredients are basically the same as those of the original drugs sold domestically and abroad.