What is Neratinib?

Neratinib (Neratinib)is an anti-tumor agent and is a potent, selective and irreversible inhibitor of human epidermal growth factor receptor type 2 (HER2), HER4 and epidermal growth factor receptor (EGFR) tyrosine kinases. Neratinib can be used alone or together with other drugs to treat early-stage HER2-positive breast cancer and is also used to treat HER2-positive breast cancer that is advanced or has spread to other parts of the body (metastatic).

Neratinib can only be used in breast cancer if a patient's tumor tests positive for a protein called human epidermal growth factor receptor 2 (HER2). HER2 protein can accelerate the growth of cancer cells. Neratinib is given afterpatients have received certain other cancer drugs. If you experience certain side effects, cancer treatment may be delayed or permanently stopped. Neratinib may cause severe diarrhea, which may be life-threatening if dehydration occurs. Patients may take anti-diarrhoeal medications for the first 2 months of treatment with neratinib.

NeratinibThe original drug is marketed in China as neratinib maleate tablets and is covered by Class B medical insurance, but reimbursement is limited to patients who meet the indications. SpecificationsThe price of each box of 40mg*180 tablets may be around 7,000 yuan. Generic drugs of neratinib are also sold overseas. The drug ingredients are basically the same as those of the original drug. The price of 40mg*180 tablets produced by Bangladesh pharmaceutical factory may be around 4,000 yuan per box (the price may fluctuate due to the exchange rate). For more information about overseas drugs and specific prices, please consult Yaode Medical Consultant.