Efficacy of Neratinib

Neratinib (Neratinib) is a breast cancer drug used to reduce the risk of recurrence in patients with early-stage breast cancer who have had surgery. It is given after treatment with trastuzumab, another drug used for the same purpose. It is designed to be used only in breast cancers that produce high levels of a protein called HER2, which helps cells divide and grow (HER2-positive breast cancer) and also has receptors (targets) for female sex hormones (hormone receptor-positive breast cancer).

In a major study involving2,840 women with HER2-positive early-stage breast cancer who had been treated with trastuzumab, neratinib was shown to be more effective than placebo, a dummy treatment, in preventing cancer recurrence. About 94% of women who received neratinib for one year lived an extra year after stopping neratinib without having their cancer come back. When only women with hormone receptor-positive cancer were considered, about 95 percent of women treated with neratinib lived another year without their cancer returning.

NeratinibThe original drug is marketed in China as neratinib maleate tablets and is covered by Class B medical insurance, but reimbursement is limited to patients who meet the indications. SpecificationsThe price of each box of 40mg*180 tablets may be around 7,000 yuan. Generic drugs of neratinib are also sold overseas. The drug ingredients are basically the same as those of the original drug. The price of 40mg*180 tablets produced by Bangladesh pharmaceutical factory may be around 4,000 yuan per box (the price may fluctuate due to the exchange rate). For more information about overseas drugs and specific prices, please consult Yaode Medical Consultant.