Should I keep taking Avatrombopag tablets?

The usage and dosage of Avatrombopag tablets should be followed as directed by your doctor. Typically, this drug is used as a long-term treatment for thrombocytopenia. Ifpatients are being treated with avatrombopag, they should take the medication regularly as recommended by their doctor and adhere to the given dosing schedule. Please do not stop or adjust the dosage of the medicine on your own to avoid affecting the efficacy or causing other adverse reactions.

Avatrombopag is an orally administered second-generation TPO-RA approved in the United States and the European Union for the treatment of primary chronic ITP in adult patients who are refractory to or inadequately responsive to other treatments, and for the treatment of thrombocytopenia in adult patients with CLD scheduled to undergo surgery. Avatropopag AUC0-inf and Cmax were not affected when avatropopag was given concomitantly with a low-fat meal or a high-fat meal. Avatrombopag reduced food exposure variability by 40% to 60%. Patients with chronic liver disease who have low platelet counts are at increased risk of bleeding. Avatrombopag safely increases platelet counts and prevents excessive bleeding during surgery.

The original drug of avatrombopag has been launched in China and has entered the scope of Class B medical insurance, but it is only reimbursed for eligible patients. The price of a common 20mg*15 tablets may be more than 7,000 yuan per box, while the original drug of avatrombopag marketed overseas is even more expensive. It is understood that there are generic drugs of avatrombopag available overseas, and their pharmaceutical ingredients are basically the same as those of the original drug. For example, the price of a box of 20mg*30 tablets in Laos pharmaceutical production specifications may be around RMB 1,000 (the price may fluctuate due to exchange rates).