The therapeutic effect of filgotinib

Three studies have shown that filgotinib (Filgotinib) is effective in improving symptoms by at least 20% in patients with moderate or severe rheumatoid arthritis. The first study involved 1,755 patients whose conditions were not adequately controlled by methotrexate,all of whom continued to take methotrexate during the study period. Seventy-seven percent of patients taking filgotinib experienced improvement in symptoms after 12 weeks.

The second study involved 448 patients whose conditions were not adequately controlled by biologic DMARDs (drugs made from living cells). All patients continued to take regular DMARDs, with approximately 80% taking methotrexate. Patients taking filgotinib showed improvement in symptoms after 12 weeks. The third study involved 1,249 patients who had not previously taken methotrexate but were at high risk of disease progression. Among patients who took filgotinib and methotrexate, 81% had improvement in symptoms after 24 weeks, compared with 78% of those who took filgotinib alone.

Figotinib is effective in treating ulcerative colitis, according to a study of patients who had or had not been previously treated with biologics. After 10 weeks of treatment, 26% of patients who had not previously used biologics and were taking filgotinib experienced mild or no symptoms. Among patients who had previously used biologics, 11% of those taking filgotinib had mild to asymptomatic symptoms. After 58 weeks, 37% of patients taking filgotinib had mild to no symptoms.

The original drug filgotinib has not yet been launched in China, and therefore is not included in medical insurance. The Bangladeshi version of the filgotinitine generic drug currently on the market overseas, specifications100mg*30 tablets may cost more than 500 yuan per box (the price may fluctuate due to exchange rates), and its drug ingredients are basically the same as those of the original drug. For more drug information and specific prices, please consult Yaode Medical Consultant.