Is mitotane a targeted drug?

mitotane is a targeted drug, a drug used for targeted treatment of advanced adrenocortical cancer. Mitotane(mitotane) is developed and produced by Bristol Myers Squibb SpA in the United States. It has remarkable therapeutic effects.

Mitotan can cause harm to the fetus. Limited postmarketing cases have been reported of preterm birth and early pregnancy loss in women treated with this product during pregnancy. Animal reproduction studies have not been conducted with mitotane. Inform pregnant women of potential risks to the fetus. The background risk of major birth defects and miscarriage in the populations shown is unknown. In the general U.S. population, the estimated background risks of major birth defects and miscarriage in clinically recognized pregnancies are 2-4% and 15-20% respectively. Mitotane is excreted in human milk; however, the effects of mitotaneon breastfed infants or on milk production are not known. Because of the potential for serious adverse reactions in breastfed infants, lactating women are advised not to breastfeed during treatment with mitotane and after interruption of treatment as long as mitotane plasma levels are detectable. Mitotanecan cause harm to the fetus if taken by pregnant women. Advise female patients of reproductive potential to use effective contraception during treatment with mitotane and after discontinuation of treatment, as long as mitotane plasma levels are detectable. Clinical studies of mitotane did not include sufficient numbers of patients aged 65 and older to determine whether they responded differently than younger patients. Other reported clinical experience has found no difference in response between older and younger patients. In general, dosage selection in elderly patients should be cautious, often starting at the lower end of the dosage range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and concomitant disease or other medications.

There are generic drugs that are officially on the market in Laos. The retail price is about 500mg100 tablets3 about one thousand. If you want to get more high-quality information, you can contact Yaode. Yade will do its best to learn more about high-quality overseas drugs for you.

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