Mitotane manufacturers

mitotane is developed and produced by Bristol Myers Squibb SpA in the United States. It is a drug used for targeted treatment of advanced adrenocortical cancer. Mitotane was approved by the USFDA in 1970 for adrenocortical cancer. 2023Year9Monday8 was approved for listing by the China National Medical Products Administration.

MitotanCommon adverse reactions during treatment include:Anorexia, nausea, vomiting and diarrhea(80%) ;Depression, dizziness or vertigo(15%-40%);Skin rash(15%);Neutropenia;Growth retardation;Hypothyroidism;Confusion;Headache;Ataxia; Spanish> pan>;Hypertriglyceridemia;Reduced blood androstenedione in women;Reduced blood testosterone;Increased sex hormone binding globulin in women and men;Reduced blood free testosterone in men. Less common adverse reactions include blurred vision, diplopia, lens opacification, retinopathy, prolonged bleeding time, hematuria, hemorrhagic cystitis, proteinuria, hypertension, orthostatic hypotension, flushing, generalized pain, pyrexia, and hypogonadism(Males) Mitotan is a strongCYP3AInducer. Concurrent use ofmitotanemay decreasethe concentrations of CYP3Asubstrates, thereby reducing the efficacy of these substrates. Avoid coadministration ofmitotanewith certainCYP3A4substrates as minimal concentration changes may result in treatment failure. If concomitant use cannot be avoided, increase the CYP3A substrate dose according to the approved product labeling.

There are generic drugs that are officially on the market in Laos. The retail price is about 500mg100 tablets3 about one thousand. If you want to get more high-quality information, you can contact Yaode. Yade will do its best to learn more about high-quality overseas drugs for you.