What cancers can mitotane treat?

Mitotane is an anti-cancer drug and the only drug approved for the treatment of inoperable or postoperative local recurrence and metastasis of adrenocortical cancer. The overall effectiveness rate is 24%.

Follow all directions on the prescription label and read any medication guides or inserts while taking mitotane. Your doctor may occasionally change the dosage, so use it exactly as directed. Frequent medical check-ups may be needed while you are taking it, and testing can help your doctor determine if mitotane is working even if you have no symptoms. Your doctor may need to give you steroid medicine or stop taking mitotane for a short time if you have a serious injury or medical emergency. Your doctor will decide when you can start taking this medicine again. Do not change your dosage or medication schedule without your doctor's advice. You must receive medical attention while taking mitotane. Store mitotane at room temperature, away from moisture and heat. If you miss a dose, take it as soon as possible, but if it is time for your next dose, skip the missed dose and do not take two doses at once. You should avoid driving or hazardous activities while taking mitotane. Sometimes it is unsafe to use certain drugs together. Some drugs can affect the blood levels of other drugs you take, which may increase side effects or make the drugs less effective. Other drugs may affect mitotane, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all the medicines you currently take and any medicines you start or stop using.

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