What are the side effects of Bedaquiline?

Bedaquiline is an antibiotic used with other drugs to treat tuberculosis that is resistant to other antibacterial drugs. Bedaquilineis suitable for adults and children at least 5 years old and weighing at least 15kg. Bedaquilinecan cause serious and sometimes fatal side effects. This medication should be used only if no other treatment options are available.

What are the side effects of bedaquiline (Bedaquiline)?

In addition to its desired effects, bedaquiline may cause some unwanted effects. Although not all of these side effects may occur, if they do, they may require medical attention. Common side effects of bedaquiline include chest pain, cough or vomiting blood, dark urine, loss of appetite, fever, fatigue or weakness, headache, itching or rash, loss of appetite, nausea and vomiting, stomach pain or tenderness, swollen feet or calves, jaundice and other symptoms.

In a placebo-controlled trial in adults, the risk of death was increased in those treated with bedaquiline compared with those treated with placebo. Bedaquiline should only be used in patients 12 years of age or older when effective treatment options are not available. QTInterval prolongation can occur, and use of other QT prolonging drugs may result in additive QT< span> prolongation, monitor the ECG and discontinue use of bedaquiline if severe ventricular arrhythmias occur or the QTc interval exceeds 500 milliseconds.

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