How long does it take to take bedaquiline to see obvious effects?

According to the recommended dosing regimen of bedaquiline (Bedaquiline) (400mg, 2 weeks, then 200mg, 3 times a week, for a total of 22 weeks) After administration, the calculated Cmax and AUC24h were 1.659μg/ml and 25.863μg*h/ml respectively. Following a single oral dose of bedaquiline, maximum plasma concentration (Cmax) is usually reached approximately 5 hours after administration.

Bedaquiline is a drug used to treat multidrug-resistant tuberculosis (MDR-TB). It is usually used in combination with other anti-tuberculosis drugs, and the dosage and duration of treatment may vary depending on the clinical situation and doctor's advice. For some patients, it may take weeks or months to see noticeable results from treatment. Patients should use the medicine correctly according to the doctor's instructions and recommendations and complete the entire course of treatment. Remember, TB is a disease that requires long-term treatment and patience until your doctor confirms improvement or recovery.

The drug is marketed in China as bedaquiline fumarate tablets and has been included in the scope of medical insurance. The common specificationsThe price of 100mg*24 tablets per box may be around 10,000 yuan, which is relatively expensive. The Russian version of bedaquiline sold overseas, Specification100mg*188 tablets per box, may cost around RMB 15,000 (the price may fluctuate due to the exchange rate). The pharmaceutical ingredients of bedaquiline sold domestically and abroad are basically the same, and there are currently no generic bedaquiline drugs on the market. For specific prices and drug information of overseas drugs, please consult Yaode Medical Consultant.