Don’t worry about the price of bedaquiline! How much does a box cost in the hospital?

Bedaquiline (Bedaquiline) is an anti-tuberculosis drug primarily used to treat multidrug-resistant tuberculosis (MDR-TB) and other tuberculosis-resistant mycobacterial infections in adults and children. It is often used in combination with other anti-tuberculosis drugs to increase the effectiveness of treatment. It is a new type of drug with a unique mechanism of action that can inhibit protein synthesis of Mycobacterium tuberculosis, thereby effectively controlling and treating tuberculosis.

Bedaquiline primarily undergoes oxidative metabolism, resulting in the formation of theN-monodesmethyl metabolite (M2) . In view of the low average exposure of M2 in the human body (23%-31%), and the anti-mycobacterial activity is lower than that of the parent compound (lower4 times-6 times), it is not considered to have a significant contribution to clinical efficacy. It should be noted that bedaquiline is a prescription drug and must be used under the guidance of a doctor. At the same time, for some patients, the use of bedaquiline fumarate may cause some adverse reactions, such as liver toxicity, toxicity, etc., so the doctor's instructions and recommendations must be strictly followed when using it.

The drug is sold in China under the name of daquiline fumarate tablets and has been included in the scope of medical insurance. The price of a common specification of 100mg*24 tablets per box may be around 10,000 yuan, which is relatively expensive. The price of the Russian version of Bedaquiline sold overseas, Specifications100mg*188 tablets per box, may be around RMB 15,000 (the price may fluctuate due to the exchange rate). The pharmaceutical ingredients of Bedaquiline sold domestically and abroad are basically the same. Currently, there are no generic bedaquiline drugs produced and marketed overseas. For specific prices and drug information of overseas drugs, please consult Yaode Medical Consultant.