How much does a box of mitotane cost to buy in Hong Kong?

Mitotane (Mitotane) is a prescription drug for adjuvant treatment that can prolong the recurrence-free survival of patients after radical resection of adrenocortical cancer. Adrenocortical carcinoma is a rare tumor characterized by a high risk of recurrence after curative resection.

Mitotane is a unique antineoplastic agent indicated exclusively for the treatment of metastatic, unresectable adrenocortical carcinoma. Mitotane has been associated with high rates of serum enzyme elevations during treatment, but has limited clinical use and has not been associated with clinically apparent cases of acute liver injury. Serum aminotransferase elevations occur in up to half of patients treated with regular doses of mitotane, but elevations up to 5 times the upper limit of normal are uncommon (<1%).

The recommended initial dose of mitotane is 2-6 grams per day, taken in divided doses, 3-4 times a day, and the dose is usually increased to 9-10 grams per day. Patients can swallow the tablets whole with a glass of water and eat them with foods that contain fat, such as milk, chocolate, oil, or cheese. Fat helps the body absorb medications.

The original drug of mitotane has been launched in China, but it has only been on the market for a short time, its purchase is very difficult, and it is not included in medical insurance. Mitotane marketed overseas The original drug has European and Turkish versions, specificationsThe price of 500mg*100 tablets per box may be more than 9,000 yuan (the price may fluctuate due to exchange rates). Mitotan generic drugs are also sold overseas, and their drug ingredients are basically the same as those of the original drug. For example, the specifications produced by Laos pharmaceutical factoriesThe price of 500mg*100 tablets per box may be more than 3,000 yuan (prices may fluctuate due to exchange rates).