Is mitotane a targeted drug or a chemotherapy drug?

Mitotane (Mitotane) is a chemotherapy drug used to treat adrenocortical cancer. It exerts its therapeutic effects by inhibiting the function of the adrenal cortex and damaging the DNA of tumor cells. Although mitotane can selectively destroy adrenocortical cancer cells, it is still classified as a chemotherapy drug because its mechanism of action is mainly to inhibit the proliferation of cancer cells by interfering with cell growth and division.

Mitotane is used to treat certain types of adrenal cancer and can reduce the production of steroids by the adrenal cortex, such as cortisol-like hormones. Mitotane is sometimes used to treat Cushing's syndrome (a condition in which the body produces too much of the hormone cortisol). Mitotane is an oral cytotoxic drug whose rapid cytotoxicity may lead to tumor infarction and bleeding. Before patients can start taking mitotane, all possible tumor tissue needs to be surgically removed from large metastases in the adrenal cortex of the cancer. If patients take mitotane before treatment, they must weigh the risks and benefits of taking this medication. If you have any unusual or allergic reaction to this drug or any other drug ingredient, please notify your doctor promptly.

The original drug of mitotane has been launched in China, but it has only been on the market for a short time, its purchase is very difficult, and it is not included in medical insurance. Mitotane marketed overseas The original drug has European and Turkish versions, specificationsThe price of 500mg*100 tablets per box may be more than 9,000 yuan (the price may fluctuate due to exchange rates). Mitotan generic drugs are also sold overseas, and their drug ingredients are basically the same as those of the original drug. For example, the specifications produced by Laos pharmaceutical factoriesThe price of 500mg*100 tablets per box may be more than 3,000 yuan (prices may fluctuate due to exchange rates).