How to take satlizumab (Anshiping)

Satralizumab (Satralizumab) is for subcutaneous use only. The recommended loading dose of satelizumab for the first three doses is 120 mg subcutaneously at weeks 0, 2, and 4, followed by a maintenance dose of 120 mg every 4 weeks. If a dose of satelizumab is missed for any reason other than elevated liver enzymes, the dose may need to be adjusted under the direction of your doctor. If a patient develops symptoms of a severe allergic reaction, the patient or caregiver should seek immediate medical attention and no further medications should be administered until self-administration has been evaluated.

Satlizumab is for patient self-administration by subcutaneous injection under the guidance of a healthcare professional (HCP). After appropriate training in subcutaneous injection technique, the patient may self-inject or the patient's caregiver may inject if the HCP deems it appropriate. Before use, remove the prefilled syringe from the refrigerator and leave it at room temperature outside the carton for 30 minutes. Instruct patients to inject the entire amount (1 mL) into a syringe that provides 120 mg of satelizumab, according to instructions. It is given by injection under the skin in the abdomen or thigh. Rotate injection sites with each dose. Do not inject into moles, scars, or areas of skin that are tender, bruised, red, hard, or incomplete.

The original drug satlizumab has been launched in China, sold under the brand name Anshiping, and is included in medical insurance. Only patients who meet the indications can be reimbursed. The specification is120mg (1ml) per box The price may be more than RMB 10,000, which is still relatively expensive; the price of each box of the original drug Saterizumab sold overseas is more than $10,000 (the price may fluctuate due to the exchange rate). The ingredients of the original drug sold domestically and abroad are basically the same. There are currently no generic versions of satlizumab available on the market.