How much does a box of domestic nintedanib cost?

Nintedanib (Nintedanib) is a drug used to treat specific types of lung diseases, mainly idiopathic pulmonary fibrosis (IPF) and chronic fibrosing interstitial lung disease (ILD) and systemic sclerosis-related interstitial lung disease (SSc-ILD). Idiopathic pulmonary fibrosis is a progressive lung disease in which a patient's lung tissue is gradually damaged, resulting in difficulty breathing and reduced quality of life. Nintedanib exerts its therapeutic effects by inhibiting multiple enzymes involved in fibrosis and tumor progression.

In China, the original drug of nintedanib has been officially launched and is sold as nintedanib ethanesulfonate soft capsules (Vegat/OFev). According to the national medical insurance policy, the drug has been included in the reimbursement scope of Class B medical insurance. This means that patients who meet the indications can enjoy certain medical insurance reimbursement when using the drug, thereby reducing the financial burden. However, it is important to note that only patients who meet the relevant indications can enjoy reimbursement, and patients who do not meet the conditions must bear all the costs themselves.

The market price of nintedanib varies depending on the packaging specifications. Common specifications are100mg*30 capsules/box and 150mg*30 capsules/box. The price of the original drug is about more than 4,000 yuan, which may be a considerable financial burden for many patients. For this reason, some domestic generic drugs have gradually appeared in the domestic market. The prices of these generic drugs are relatively close to the people, usually more than 2,000 yuan per box. Although the ingredients of these generic drugs are basically the same as those of the original drugs, patients still need to pay attention to the reputation of the manufacturer and the quality of the drugs when choosing.

In addition to domestic generic drugs, some foreign generic drugs are also available. For example, the price of nintedanib produced by India's BDR Company, Grammark Pharmaceuticals, Laos ASEAN Pharmaceuticals and other manufacturers is usually around 600 yuan. However, due to the impact of exchange rate fluctuations, the actual selling prices of these foreign drugs may change, so patients should understand the current market prices in advance when purchasing.

Reference materials:https://www.mayoclinic.org/drugs-supplements/nintedanib-oral-route/description/drg-20122674