雷洛昔芬(Evista)现在最新价格多少钱一盒

Raloxifene (Evista) is an important drug for the treatment of postmenopausal osteoporosis and is a selective estrogen receptor modulator. Not only does it increase bone density, it also reduces the risk of invasive breast cancer in high-risk women.

How much is the latest price of a box of raloxifene (Evista)

Raloxifene has been on the market in China for many years and has been included in the national medical insurance directory, which greatly reduces the financial burden of patients.

Specifications and Prices

There are currently two versions mainly circulating in the market: the version produced by Japan's Nippon Medical Industry Co., Ltd. has a specification of 60 mg × 100 tablets/box, and the price is about US$42; the American Eli Lilly version has the same specifications, and the price is about US$70. Out-of-pocket expenses will be significantly reduced after medical insurance reimbursement, and the specific amount varies depending on regional policies.

How to take it

Take 1 tablet (60mg) orally at a fixed time every day, before or after meals. It is recommended to combine calcium supplements (1500mg daily) and vitamin D (400-800IU daily) to strengthen bone health. If you forget to take the medicine within 12 hours, you can take it immediately. If it exceeds 12 hours, skip the dose.

Please maintain regular follow-up visits during medication. The doctor will adjust the treatment plan based on changes in bone density.

What are the special medication groups for raloxifene (Evista)?

Certain groups of people need to be particularly cautious when using raloxifene. Be sure to inform your doctor about your health status before taking the medication.

Pregnant women and women of childbearing age

It is absolutely prohibited for pregnant women. Animal experiments show that it may cause fetal malformation or miscarriage. Breastfeeding women are also prohibited from using it as the drug ingredients may affect the development of the baby through breast milk. It is not recommended for women who are not yet menopausal (including perimenopausal women). This drug is only suitable for women who have natural or surgical menopause.

Patients with risk of thrombosis

Patients with a history of venous thrombosis such as deep vein thrombosis and pulmonary embolism must be strictly prohibited. People who are bedridden for a long time, have recently undergone major surgery, or suffer from severe varicose veins need a doctor to assess the risks before use. The first 4 months of treatment is a period of high incidence of blood clots. During this period, leg swelling, chest pain or difficulty breathing require immediate medical attention.

Patients with moderate to severe renal insufficiency need to adjust the dosage and strengthen monitoring. Use with caution in patients with abnormal liver function. Patients with cardiovascular and cerebrovascular diseases need to be alert to the increased risk of stroke, especially postmenopausal women with hypertension and diabetes.

Precautions for Raloxifene (Evista)

Correct use of the drug can maximize the efficacy and reduce risks. Please focus on the following matters:

Adverse reactions that you must be alert to

Some patients will experience hot flashes. It is recommended to wear breathable clothing and avoid spicy food and alcohol. Some patients may experience leg cramps, which can be relieved by soaking their feet in warm water and supplementing magnesium before going to bed.

If unilateral calf swelling and pain, sudden dyspnea or chest pain occur, it indicates that venous thromboembolism may occur and requires immediate emergency treatment.

Monitoring requirements during treatment

Bone density should be reviewed every 3 months during initial treatment, and once a year after stabilization. Test liver and kidney function indicators every 6 months. Abnormal uterine bleeding requires immediate gynecological examination. People at high cardiovascular risk are recommended to monitor blood pressure and blood lipids every quarter. If you need to undergo orthopedic surgery during treatment, please inform your doctor in advance that you are taking this medicine.

Pharmaceuticals should be stored in a dry environment at 20-25°C, away from direct sunlight. After unpacking, the tablets should be kept in the original aluminum foil to prevent moisture and deterioration.