雷洛昔芬(Evista)各版本的购买渠道

Raloxifene (Evista) can be used for the treatment and prevention of postmenopausal osteoporosis. It can also reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and the risk of invasive breast cancer in postmenopausal high-risk women.

Purchase channels for various versions of raloxifene (Evista)

Raloxifene has been officially launched in mainland China and is included in the scope of medical insurance reimbursement. Patients can obtain it through the following formal channels.

Hospital pharmacies and chain pharmacies

Large hospital pharmacies can purchase raloxifene with a prescription, and large chain pharmacies may also have raloxifene in stock. When purchasing medicines, please choose a regular hospital to avoid buying fake and shoddy drugs.

Online formal platform

If patients want to purchase raloxifene more conveniently without leaving home, they can choose an online formal platform, which supports prescription upload and review. Please choose a formal platform when purchasing drugs.

Does raloxifene (Evista) cause side effects?

Some patients will experience tolerable side effects after taking the drug, and timely intervention can effectively control the symptoms.

Common reactions and countermeasures

A common reaction is hot flashes. Patients can wear breathable cotton underwear and avoid triggers such as chili pepper/alcohol. Some patients experience leg cramps. Soak your feet in warm water for 15 minutes before going to bed, and raise your feet 10 cm while sleeping. Some patients may experience joint pain. Use a 40°C hot compress pad 3 times a day (20 minutes each time) and swim 2-3 times a week to reduce the load on the joints.

Emergency treatment of serious complications

Some patients may develop venous thromboembolism, which occurs most frequently 4 months before treatment. When unilateral calf swelling and fever or chest pain makes breathing difficult, lie down immediately and call an ambulance.

< p>Some patients may have signs of stroke, sudden distortion of the mouth, numbness of the limbs, or confusion of speech. At this time, any oral medication is prohibited, and the airway should be kept open to wait for rescue.

What are the special groups for taking raloxifene (Evista)?

The following groups need to be strictly evaluated by a doctor to decide whether to take the drug.

Pigies that are absolutely contraindicated

<. p>Contraindicated for pregnant and lactating women (risk of fetal malformation). Contraindicated for premenopausal women (including perimenopausal women). Contraindicated for patients with active thrombosis (acute stage of deep vein thrombosis/pulmonary embolism). Contraindicated for patients with severe hepatic and renal insufficiency (transaminases >3 times the upper limit or creatinine clearance rate <30mL/min).

High-risk groups

Patients with a history of thrombosis. Treatment needs to be restarted after 3 months. Patients with cardiovascular and cerebrovascular diseases (with a history of coronary heart disease/cerebral infarction) are recommended to use anticoagulants prophylactically. People with high risk of breast cancer (BRCA gene mutations) need to have breast ultrasound reviewed every six months.

Patients with moderate liver damage (Child-Pugh) Level B) The dose is reduced to 30 mg/day, and patients with renal insufficiency (eGFR 30-45 mL/min) do not need to adjust the dose, but creatinine clearance needs to be monitored every quarter.

During treatment, bone density changes must be detected for the first 3 months, liver and kidney function, and coagulation should be reviewed every 6 months. Breast ultrasound and gynecological examinations should be performed every year. If visual abnormalities occur, ophthalmology should be sought immediately.