塞来昔布的安全性及疗效

Celecoxib (Celebrex) is a new generation compound with a unique mechanism of action that specifically inhibits cyclooxygenase-2 (COX-2). Inflammatory stimulation can induce the production of COX-2, thus leading to the synthesis and accumulation of inflammatory prostaglandins, especially prostaglandin E2, causing inflammation, edema and pain. It can prevent the production of inflammatory prostaglandins by inhibiting COX-2 to achieve anti-inflammatory, analgesic and antipyretic effects.

Indications for celecoxib include: 1) For the relief of symptoms and signs of osteoarthritis. 2) For the relief of symptoms and signs of rheumatoid arthritis in adults. 3) For the treatment of acute pain in adults.

What is the safety and efficacy of celecoxib?

A new study shows that Pharmacia and Pfizer's COX-2 specific inhibitor celebrex (celecoxib capsules) can specifically reduce pain and improve joint function in patients with ankylosing spondylitis (AS). The disease, which mainly affects young men, causes severe pain and weakens the patient's joints.

Celecoxib (Celebrex) is the only COX-2 specific inhibitor that can treat osteoarthritis and rheumatoid arthritis in adults, one of the most severe forms of arthritis. Celecoxib has not previously been used to treat ankylosing spondylitis.

According to the leader of the study, rheumatologist Maxime Dougados of Cochin in Paris, France, this study demonstrates the effectiveness of treating the pain and inflammation caused by ankylosing spondylitis, which is meaningful because there are currently few treatment options for this disease. Although further research is needed, the current findings suggest that celecoxib may be an effective new treatment for this serious chronic disease.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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