非布司他的价格是多少？

It belongs to the class of drugs that inhibit the production of uric acid. These drugs will cause more or less side effects on the human body. For example, long-term use of benzbromarone may cause kidney damage, allopurinol damages the liver, and febuxostat is the latest drug with the smallest side effects. Of course, febuxostat is also the most expensive. Febuxostat is also known as Febuxostat. Febuxostat and Febuxostat are the same drug, but their names are different due to translation issues. Febuxostat is a new and highly effective selective inhibitor of non-purine xanthine oxidase, a key enzyme that promotes uric acid production. Febuxostat is the latest XOR inhibitor developed in the world. It acts highly selectively on this oxidase to reduce the synthesis of uric acid in the body and lower the concentration of uric acid, thereby effectively treating gout.   

Among drugs that inhibit uric acid production, colchicine is mainly used in the acute phase (acute phase). Compared with febuxostat, allopurinol is mainly used. Compared with allopurinol, febuxostat has less side effects and has the following advantages: 1. Allopurinol only inhibits reduced XOR, while febuxostat has a significant inhibitory effect on both oxidized and reduced XOR, so its uric acid-lowering effect is more powerful and long-lasting; 2. Since allopurinol is a purine analog, it will inevitably affect the activities of other enzymes involved in purine and pyridine metabolism. Therefore, repeated high-dose administration is required to maintain high drug levels during allopurinol treatment. This also leads to serious or even fatal adverse reactions due to drug accumulation. Febuxostat is a non-purine XOR inhibitor and therefore has a better safety profile. 

Febuxostat can reduce uric acid levels in the blood of gout patients with hyperuricemia. The dosage of febuxostat is 40 mg or 80 mg once daily. However, this product is not recommended for gout patients without hyperuricemia. The domestic price of febuxostat is 10$/tablet, one tablet a day, which is about 300 per month. However, some patients do not have good results and need two tablets a day, which is about 600 per month. Gout requires febuxostat for a long time, which is not a small number. The current emergence of febuxostat in India has greatly reduced the burden on patients. The Indian specification is 80mg*30 tablets/box and only costs 200$.