非布索坦治疗效果如何？

It is a uric acid-lowering drug produced by the Japanese company TAKEDA, and can also be translated as febuxostat. So, what is the therapeutic effect of febuxostat?

Febuxostat is a drug that inhibits the production of uric acid. It has a significant inhibitory effect on both oxidized and reduced xanthine oxidoreductase, and its effect on reducing uric acid is more powerful and lasting. It can be used to treat chronic hyperuricemia of gout, especially in patients with joint tophi. Long-term use can make tophi shrink or even disappear.

Febuxostat is very effective in reducing uric acid in the human body, and the effect is very fast. After taking Febuxostat, uric acid can be reduced to an ideal value.

In addition, the main goal of gout treatment is to reduce blood uric acid levels. Currently, the three most commonly used clinical urate-lowering drugs in my country are allopurinol, benzbromarone, and febuxostat. So, why is febuxostat my first choice for urate-lowering treatment? What are the pros and cons of Febuxostat?

Currently, uric acid-lowering drugs are divided into two categories: one is a drug that promotes uric acid excretion. Its function is to promote the kidneys to "run faster" and increase the excretion of uric acid. The representative drug is "benbromarone". This drug is relatively cheap and has few side effects. Unfortunately, gout itself can cause renal insufficiency. Because this drug makes the kidneys "run faster" and may worsen the already poor kidney function, medical guidelines from various countries do not recommend it as the first choice. It cannot be used for patients with existing renal insufficiency and patients with urinary system stones.

The other type is drugs that inhibit the production of uric acid. They can directly inhibit the production of uric acid in the body without increasing the burden on the kidneys. They are the drugs recommended by the guidelines of various countries. There are currently two types of this drug: allopurinol and febuxostat. Allopurinol has a better effect on some patients. Unfortunately, the incidence of allergy to allopurinol is high, and allopurinol can cause serious adverse reactions, and some severe patients can die. Therefore, this drug is relatively dangerous, so it has become the first choice!