非布索坦效果如何呢?
When patients come into contact with a gout treatment drug, they first need to know: whether the drug is used to lower uric acid or treat acute arthritis. For example, colchicine is a drug used to treat acute arthritis; like allopurinol and benzbromarone, its effect is to lower uric acid. So, what is the therapeutic effect of febuxostat?
Allopurinol and febuxostat are classified into one category because they both reduce the synthesis of uric acid, while benzbromarone increases the excretion of uric acid and are classified into another category.
Because there are certain differences in the populations that these two types of drugs are applicable to, when evaluating their efficacy, we often compare the uric acid-lowering effects of allopurinol and febuxostat.
According to current domestic and foreign studies, febuxostat has the same uric acid-lowering effect as allopurinol, or even slightly better than allopurinol.
Allopurinol has been able to "ride the battlefield" in the field of gout treatment for so many years. Its efficacy is very certain, and it is often used as a comparison for new drugs on the market.
Patients may think that the uric acid-lowering effect of febuxostat is only equivalent to or slightly better than that of allopurinol, and it is not a big improvement! However, although both have similar uric acid-lowering effects, febuxostat has some unique advantages compared with allopurinol.
Allopurinol may cause hypersensitivity reactions, or even very serious drug rashes that may lead to patient death. Although febuxostat may also cause drug rash, it is significantly less severe than allopurinol.
Febuxostat is mainly metabolized in the liver. A considerable number of gout patients suffer from renal insufficiency or kidney stones. In this case, Febuxostat is a very good choice.
Therefore, febuxostat is safer than allopurinol and is more suitable for patients with renal insufficiency and kidney stones.
Compared with allopurinol, febuxostat has a very good effect on reducing uric acid. Therefore, its therapeutic effect has been affirmed. It is safer than allopurinol and is more suitable for patients with renal insufficiency and kidney stones. However, you still need to pay attention to skin rash and liver and kidney function during medication.
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