爱尔兰爵士制药的去纤苷在中国上市了吗？

(Defibrotide) is a single-stranded oligonucleotide mixture with antithrombotic and fibrinolytic effects, used to treat severe veno-occlusive disease (VOD) in adults and children who have received chemotherapy and stem cell transplantation. It can increase fibrin lysis and modulate platelet activity to reduce procoagulant activity. It has not been reported to increase the risk of bleeding. 

Some foreign researchers first reported the efficacy and prognosis of clinical application of defibrinated sodium in the United States. The results showed that the drug significantly improved the patient's prognosis and survival time. Over time, multiple studies have been reported to confirm the effectiveness of defibrotide sodium in HVOD, including a multi-center clinical study in Europe that showed that 55% of patients were in complete remission; 43% of patients were alive after 100 days of treatment. So, has Irish Jazz Pharmaceuticals’ defibrotide been launched in China?

In foreign countries, defibrotide has been on the market for many years, but it has not yet been approved for domestic marketing, and it has not been included in medical insurance. This means that currently, patients can only choose to purchase drugs overseas for use. In foreign countries, the price of defibrinated sodium is 21,600$/box, and the specification is 200mg/box. Since its price will also change due to exchange rate fluctuations, patients who want to know more about its specific price or want to purchase this drug can consult with the domestic professional and formal overseas medical service organization Medical Companion Travel.

Jazz Pharmaceuticals, an Irish R&D-based biopharmaceutical company, announced last year that it will use Codiak BioSciences' enaExTM precision engineering platform to research, develop and commercialize cancer exosome therapies. This cooperation may bring Codiak more than $1 billion in revenue. As one of the products of Irish Jazz Pharmaceuticals, although it has not yet been launched in China, patients can purchase medicines overseas through Medical Companion Travel.

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