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爱尔兰爵士制药的去纤维钠多少钱一瓶?

Author: Medicalhalo
Release time: 2025-10-19 11:44:20

It is indicated for the treatment of adults and children with hepatic veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome (SOS), and renal or pulmonary dysfunction after hematopoietic stem cell transplantation (HSCT).

Defibrotide (Defibrotide sodium) is a mixture of single-stranded oligonucleotides with anti-thrombotic and fibrinolytic effects. In recent years, multiple clinical research results have shown that defibrotide is a safe and effective drug for preventing and treating HVOD. In vitro, defibrinoside enhances the enzymatic activity of plasmin that hydrolyzes fibrin clots, increases tissue plasminogen activator (t-PA) and thrombomodulin expression, and decreases von Willebrand factor (vWF) and plasminogen activator inhibitor-1 (PAI-1) expression, thereby reducing EC activation and increasing EC-mediated fibrinolysis. Defibrotide protects ECs from chemotherapy, tumor necrosis factor-α (TNF-α), serum starvation, and perfusion-induced injury.

Defibrinated sodium is developed and produced by Jazz Pharmaceuticals. Jazz Pharmaceuticals Public Limited Company (NASDAQ: JAZZ) was founded in 2003 and is headquartered in Dublin, Ireland. It is a commercial-stage biopharmaceutical company. How much does a bottle of defibrinated sodium cost from Jazz Pharmaceuticals in Ireland?

At present, it has not been officially launched in the country. Medical Travel has learned that Irish Jazz Pharmaceuticals’ Defibrinated Sodium is exported to Turkey and the price of a 200mg bottle of Defitelio is about $22,000. For more drug price information, please consult customer service.

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