去纤苷是哪个国家产的,中国上市了吗？

Hepatic veno-occlusive disease (HVOD), also known as hepatic sinusoidal obstruction syndrome (HSOS), is a liver vascular disease that mainly causes hepatocyte atrophy and diffuse liver fibrosis caused by endothelial cell damage in the terminal hepatic lobular veins. It is a non-thrombotic obstruction of the hepatic circulation. There are many causes of the disease. In 1920, it was reported that hepatic sinusoidal congestion and hemorrhagic necrosis in the central area of ​​the liver lobules caused by dog ​​tongue poisoning. It was first reported by Hill et al. in 1953, and later named HVOD by Bras et al. In 2002, Deleve et al. renamed it hepatic sinusoidal obstruction syndrome. This disease is rare in clinical practice, and its clinical manifestations are not very specific, making it easy to be misdiagnosed or missed. (Defibrotide) is a mixture derived from pig intestinal mucosa. Its mechanism of action is not yet fully understood, but it has fibrinolytic effect and protects endothelial cells. So, which country is defibrinoside produced in? Is it on the market in China?

Which country is defibrinoside produced in?

Manufacturer of defibrotide: developed by Gentium Pharmaceuticals in Italy. Defibrotide is a mixture derived from porcine intestinal mucosa. Its mechanism of action is not yet fully understood, but it has fibrinolytic effects and protects endothelial cells. It increases fibrin lysis and modulates platelet activity to reduce procoagulant activity. It has not been reported to increase the risk of bleeding.

Has defibrinoside been launched in China?

Defibrotide is not currently on the market in China, so domestic patients may be disappointed. However, I believe that in the near future, defibrotide will be on the market in China, which will bring good news to the majority of patients. However, before that, patients still need to use this drug for treatment. Therefore, patients can choose domestic and overseas medical service organizations Medical Companions to help you purchase defibrotide.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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