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Esomeprazole is a proton pump inhibitor and is often used in combination with antibacterial drugs to form triple or quadruple therapy to treat peptic ulcers. How much does esomeprazole cost?

Price of esomeprazole: According to Medical Companion Travel, the Japanese version of esomeprazole is about 1,900, and the Indian version is about 500. Since exchange rates fluctuate and prices are not fixed, please consult Medical Travel for specific prices.

Esomeprazole reduces gastric acid secretion through a specific targeting mechanism and is a specific inhibitor of proton pumps in parietal cells. The R-isomer and S-isomer of esomeprazole have similar pharmacodynamic properties.

How to take esomeprazole:

1. When taking esomeprazole, the tablet should be swallowed whole together with the liquid. It should not be chewed or crushed, otherwise it will affect the efficacy of the medicine. For patients who cannot swallow, esomeprazole can be dissolved in carbonate-free water and administered through a gastric tube.

2. Gastroesophageal reflux disease (CERD): For erosive reflux esophagitis, 40 mg/d for 4 to 8 weeks; after cure, maintain treatment with 20 mg/d to prevent recurrence. If there are only symptoms but no inflammation, 20 mg/d is given. After the symptoms are relieved, the drug can be taken as needed, 20 mg/d.

3. Eradication of Helicobacter pylori in peptic ulcer disease is the basis for long-term remission of peptic ulcer disease. For duodenal ulcer, 20 mg is used in combination with two antibiotics, mostly amoxicillin 1.0 and clarithromycin 0.5, 2 times/d. The treatment course is 7 days. For patients with active ulcer disease, single drug treatment is usually given to ensure symptom relief and ulcer healing. The ulcer healing rate was 90% after 4 weeks. As effective as omeprazole in relieving upper abdominal pain.

4. For gastrinoma (Zerollis-Ellison syndrome), the recommended starting dose is 40 mg/d. Then, the dose should be adjusted individually and the course of treatment determined based on clinical manifestations.

5. The triple combination of esomeprazole and antibiotics is used to eradicate Hp. Nexium 20mg amoxicillin 1g and clarithromycin 500mg, 2 times a day for 7 days, the eradication rate is 89%.