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鲁索替尼乳膏效果如何?使用鲁索替尼乳膏需注意什么?

Author: Medicalhalo
Release time: 2025-10-19 11:44:20

The best treatment for atopic dermatitis is to use ointments with significant effects. This can ensure that patients have more significant effects during treatment. Ruxolitinib cream is a drug that has been used more frequently in the clinical treatment of atopic dermatitis in recent years. It is also a drug that most patients want to learn more about. Let us learn more about ruxolitinib cream in detail.

How effective is ruxolitinib cream?

In a Phase III clinical trial in Japan in patients with atopic dermatitis aged 16 years and older, the primary endpoint of efficacy was "* at final assessment mEASI” score. Ruxolitinib Cream 0.5% was confirmed to be superior to placebo and the safety of long-term administration was also confirmed.

The proportion of patients with mEASI-50 was 51.9% (55 of 106) in the digotinib group and 11.5% in the vehicle group. The proportion of patients with mEASI-75 was 26.4% (28 of 106 patients) and 5.8% (3 of 52 patients) in the placebo group.

The proportion of patients with an improved AD Dermatitis Area and Severity Index (mEASI) score that improved by at least 50% or at least 75% at the end of treatment.

What should I pay attention to when using ruxolitinib cream?

Patients need to note that if there is infection, wound or mucous membrane in the wound, do not use it on the affected area to avoid secondary damage to the wound. At the same time, ruxolitinib cream is not sure to be harmful to children under two years old, so it is prohibited to use it by children under two years old. At the same time, pregnant women and lactating patients should not use ruxolitinib cream.

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