Inbec治疗艾滋病疗效如何呢？

Trimax () is a compound preparation. Each tablet contains dolutegravir sodium (calculated as dolutegravir) 50 mg, abacavir sulfate (calculated as abacavir) 600 mg and lamivudine 300 mg. It is suitable for the treatment of adults infected with human immunodeficiency virus (HIV) and adolescents over 12 years old (with a weight of at least 40 kg). On January 22, 2018, it was officially launched in mainland China.

Inbec is the first single-pill compound preparation with a complete treatment plan in the field of HIV treatment in mainland China. How effective is it?

Judging from a large number of clinical trial data, DTG has a low discontinuation rate due to adverse drug reactions (ADR) or virological failure, which are 5.8% and 0.5% respectively. The ADR drops significantly after one year of taking the drug. The most common adverse reactions are gastrointestinal dysfunction, mental disorders and neurological disorders, but the adverse reaction rates are less than 1.5%. From the comparison with patients who failed the first-line treatment of the other two integrase inhibitors RAL (Ascent) and EVG (elvitegravir), Inbec (Inbec) has significantly fewer resistance mutation sites than the other two drugs, making it less likely to develop resistance.

AIDS is an infectious disease that can be transmitted through sexual contact, blood, and mother-to-child transmission. Currently, there is still a lack of effective drugs to cure HIV infection worldwide. It can only reduce the viral load to the maximum and lasting extent and improve the patient's quality of life. HIV-infected patients, regardless of race, should be screened for the HLA-B5701 allele before starting treatment with abacavir-containing products. If the patient is known to carry the HLA-B5701 allele, he should not take products containing abacavir.

Suimeike () is a compound preparation that can achieve the effect of combined medication by taking one drug. The antiviral effect of this drug is similar to that of tenofovir, but it has less damage to mitochondria, thereby reducing fat consumption, pancreatitis, neuritis, lactic acidosis and other adverse reactions. It has the characteristics of high efficacy, good tolerance, high resistance barrier and few drug interactions.