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(Inbec) is a three-in-one compound drug for the treatment of HIV. It is the first single-pill compound preparation with a complete treatment plan in the field of HIV treatment in mainland China. It has the characteristics of high efficiency, good tolerability, high resistance barrier and few drug interactions. AIDS is an extremely harmful infectious disease caused by infection with the AIDS virus (HIV). HIV is a virus that attacks the body's immune system. It takes the most important CD4 T lymphocytes in the human immune system as its main attack target, destroys these cells in large quantities, and causes the human body to lose its immune function. Therefore, the human body is susceptible to various diseases, and malignant tumors can occur, with a high mortality rate.

The ingredients of dolutegravir tablets are dolutegravir 50mg + abacavir 0.6g + lamivudine 0.3g. These three drugs are used for the treatment of HIV-1 infection. It is the only three-in-one compound drug containing dolutegravir. It is suitable for the treatment of adults and adolescents over 12 years old (with a weight of at least 40kg) infected with human immunodeficiency virus (HIV).

Dolutegra is a compound preparation that can achieve the effect of combined medication by taking one drug. The antiviral effect of this drug is similar to that of tenofovir, but it has less damage to mitochondria, thereby reducing fat consumption, pancreatitis, neuritis, lactic acidosis and other adverse reactions.

Dolutegravir in the ingredient can inhibit HIV integrase by binding to the active site of integrase and blocking the strand transfer step of reverse transcription deoxyribonucleic acid (DNA) integration (a key step in the HIV replication cycle). Abacavir is a carbocyclic synthetic nucleoside analogue. Abacavir is converted into the active metabolite carbavir triphosphate (CBV-TP), a deoxyguanosine-5'-triphosphate (dGTP) analogue, under the action of intracellular enzymes. CBV-TP inhibits the activity of HIV-1 reverse transcriptase (RT) by competing with the natural substrate dGTP and inserting into viral DNA. Lamivudine is a synthetic nucleoside analogue. Lamivudine is phosphorylated in cells to generate the active 5-triphosphate metabolite, lamivudine triphosphate (3TC-TP). The main mode of action of 3T-CTP is to terminate DNA chain synthesis by inserting nucleotide analogs, thereby inhibiting RT activity.