What are the main side effects of collagenase ointment? What to pay attention to

Collagenase ointment is indicated for debridement of chronic skin ulcers and severely burned areas. The optimal pH range for collagenase is 6-8. Since collagen accounts for 75% of the dry weight of skin tissue, the ability of collagenase ointment (Collagenase) to digest collagen within the physiological pH and temperature range makes it particularly effective at removing debris. Clinical trials have proven the efficacy of this drug: Collagenase ointment (Collagenase) can effectively remove necrotic tissue from deep second-degree burn wounds, accelerate wound healing, and have a positive effect on the patient's condition. But like most drugs, treatment with this drug will also produce some side effects. What are the main side effects? What should I pay attention to?

Collagenase ointment was well tolerated. Possible adverse reactions include local pain, burning, tingling, etc. Because each patient's physical condition and condition are different, the side effects produced after receiving collagenase ointment (Collagenase) treatment will also be different. The specific side effects are mainly determined by the patient's condition, personal constitution, and tolerance to the drug. If patients experience serious side effects during treatment with collagenase ointment (Collagenase), they should seek medical help immediately.

Precautions for Collagenase Ointment

When debridement of necrotic tissue is completed and granulation tissue is well established, use of collagenase ointment (Collagenase) should be stopped. Occasionally, slight temporary erythema may occur when collagenase ointment is applied to surrounding tissue outside the wound, so the ointment should be applied carefully to the wound.

Antibiotics should be applied to the wound before applying Collagenase ointment. If the infection does not respond, treatment with Collagenase ointment should be discontinued until the infection resolves.

People with local or systemic allergies to the ingredients contained in Collagenase ointment should not use this drug for treatment.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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