What kind of medicine is celecoxib? What disease does it cure?

What kind of medicine is celecoxib? What disease does it cure? (Celebrex) capsules are indicated for the relief of the signs and symptoms of osteoarthritis, for the relief of the signs and symptoms of rheumatoid arthritis in adults, and for the treatment of acute pain in adults, based on each patient's treatment goals.

As a non-steroidal anti-inflammatory analgesic, celecoxib is a cyclooxygenase 2 inhibitor, which has less irritation to the gastric mucosa and has better gastrointestinal tolerance in patients who use it. But even so, long-term use is not recommended in the absence of contraindications and obvious adverse reactions. It is recommended to reduce the dosage and discontinue use in time after the joint symptoms improve.

Celecoxib inhibits prostaglandin production by inhibiting cyclooxygenase-2 and plays anti-inflammatory, anti-rheumatic, and analgesic effects. It is mainly suitable for relieving joint symptoms such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis; it can also treat acute pain, such as acute ankle sprain, acute shoulder tendinitis, bursitis, etc. Osteoarthritis and rheumatoid arthritis can be used for 2-4 weeks; for ankylosing spondylitis, if there is no effect after taking it for 4 weeks, you can follow the doctor's advice to increase the dose appropriately and take it for a while. If it still doesn't work, you need to go to the rheumatology and immunology department in time to change the treatment plan under the guidance of a professional doctor.

Long-term use of celecoxib (Celebrex) may cause serious cardiovascular thrombotic adverse events, an increased risk of myocardial infarction and stroke, the risk of which may be fatal. In the APC trial, compared with placebo, the relative risk (RR) of the composite endpoint of cardiac death, myocardial infarction or stroke was 3.4 (95% CI: 1.4-8.5) for 400 mg twice daily and 2.5 for celecoxib 200 mg twice daily. In two large, controlled clinical trials using other COX-2 selective NSAIDs to treat pain in the first 10-14 days after CABG surgery, an increased incidence of myocardial infarction and stroke was found.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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