What does collagenase ointment do? What are the usage and side effects?

In deep second-degree burns, tissue necrosis reaches the dermis. The persistence of necrotic tissue hinders epithelial crawling, can also easily cause bacterial infection, aggravate inflammatory reactions, and hinder wound repair. Therefore, the first step in repairing burn wounds is to remove necrotic tissue. Complete debridement often results in loss of adjacent normal tissue, while incomplete debridement is the source of postoperative infection. Research in recent years has found that in addition to having a good scab removal effect, it can also accelerate the response of repair cells to damage and promote wound healing.

So, what does collagenase ointment do? Collagenase can act on denatured collagen, and can also act on undenatured collagen fibers between necrotic tissue and normal tissue, which can remove necrotic tissue more thoroughly.

How to use collagenase ointment and what are its side effects?

: Before using collagenase ointment, soak the gauze pad with physiological saline, or use a cleanser compatible with collagenase ointment to wipe the debris and digestion on the wound, and finally rinse with physiological saline. In the event of an infection, patients can use an appropriate topical antibiotic powder. At this point, you can start to apply collagenase ointment, either directly on the wound or on a sterile gauze pad to fix the wound position.

: Collagenase ointment is well tolerated and has very few side effects. Side effects that may occur rarely include local pain, stinging and burning sensations in the wound. It is recommended that patients carefully follow the doctor's instructions when using it and use the medicine correctly to make the wound heal faster.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.