维利西呱用法用量是多少,服药后几小时见效？

Vericiguat is the first sGC agonist to achieve positive results in the treatment of heart failure targeting the NO-sGC-cGMP pathway. It has good pharmacokinetic characteristics, low risk of drug interaction, high safety, and is suitable for combined drug treatment of patients with heart failure with multiple comorbidities. On January 19, 2021, Veliciguat was approved by the U.S. Food and Drug Administration (FDA) for the purpose of reducing cardiovascular disease in adult patients with symptomatic chronic heart failure with LVEF <45% who are hospitalized for heart failure or require outpatient intravenous diuretic treatment. Risks of death and hospitalization for heart failure. The marketing application in China has been officially included in priority review as "clinically urgently needed shortage drugs, innovative drugs and improved new drugs for the prevention and treatment of major infectious diseases, rare diseases and other diseases", providing a new treatment option for patients with worsening chronic heart failure. So, what is the dosage of Vericiguat and how many hours does it take for it to take effect?

What is the dosage of Vericiguat?

The recommended starting dose of veliciguat is 2.5 mg taken orally daily with food. The dose of veliciguat should be doubled approximately every 2 weeks to achieve the patient's target maintenance dose of 10 mg per day. For patients who have difficulty swallowing, the tablets may be crushed and mixed with water.

Vericiguat takes effect within a few hours after taking it

The patient's disease progression, personal constitution, and drug tolerance are different, and the onset time and therapeutic effect after receiving vericiguat treatment will also be different. Therefore, the effective time of vericiguat cannot be accurately given. How long it takes for the patient to see the effect after treatment with vericiguat is mainly determined by the patient's personal constitution, disease progression, and tolerance to the drug.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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