伊伐布雷定(Ivabradine)的作用和副作用是怎样的?

Ivabradine is FDA-approved in the United States for the treatment of symptomatic patients with stable heart failure and an ejection fraction of 35% or less, to reduce the risk of hospitalization due to worsening heart failure. Ivabradine blocks the flow of electricity from the pacemaker that regulates heart rate. This results in prolonged diastolic time and decreased heart rate.

What Ivabradine does

Ivabradine belongs to a class of drugs called hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. It works by slowing down the heart rate so that the heart can pump more blood through the body with each beat. Ivabradine is used to treat certain adults with heart failure (a condition in which the heart cannot pump enough blood to the rest of the body) to reduce the risk of the condition getting worse and requiring treatment in the hospital. Ivabradine is also used to treat a certain type of heart failure caused by cardiomyopathy (a condition in which the heart muscle weakens and enlarges) in children 6 months and older.

Instructions for use of Ivabradine

Ivabradine is available for oral administration in tablet and oral solution (liquid) forms. Usually taken twice daily with food. Take ivabradine at about the same time every day. Ivabradine can control the symptoms of heart failure but does not cure heart failure, and patients should continue taking it even if they feel well. Do not stop taking Ivabradine without talking to your doctor.

Ivabradine (Ivabradine) side effects

Common side effects include fast, irregular or violent heartbeat, slow or stopped heartbeat, chest pain or pressure, worsening shortness of breath, dizziness, excessive fatigue, swelling of the face, throat, tongue, lips and eyes, difficulty swallowing or breathing, hoarseness, etc. The patient's physique and condition are different, and the side effects after taking the drug are also different.

Handling the side effects of Ivabradine

If your heartbeat is fast, irregular or violent, you can try taking deep breaths to relax your body and relieve tension. If symptoms persist or worsen, seek medical attention promptly.

If the heartbeat slows or stops, you should seek medical treatment immediately and take appropriate treatment measures, such as using a pacemaker.

If you experience chest pain or pressure, try taking deep breaths and relaxing your body. If symptoms persist or worsen, seek medical attention promptly.

If shortness of breath worsens, the airway should be kept open and excessive activities or tension should be avoided as much as possible. If symptoms persist or worsen, seek medical attention promptly.

In case of dizziness or excessive fatigue, you should rest for a while to relieve symptoms. If symptoms persist or worsen, seek medical attention promptly.

If you have swelling of the face, throat, tongue, lips and eyes, difficulty swallowing or breathing, or hoarseness, you should seek medical attention immediately and take appropriate treatment measures.

When side effects occur during Ivabradine treatment, appropriate measures should be taken according to the symptoms to relieve the symptoms. If symptoms are severe or last for a long time, seek medical attention promptly. At the same time, when using ivabradine, you should follow the doctor's advice, pay attention to physical changes, and conduct regular review and evaluation.

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