Planep效果怎样？

It is a new type of selective aldosterone receptor blocker that can effectively control high blood pressure, reduce damage to target organs such as the heart, brain and kidneys, and improve microalbuminuria in patients with type 2 diabetes. So, what is the effect of Planep?

Planep’s therapeutic effects:

A new analysis of the large-scale clinical study Evaluating Planep in Heart Failure Patients (EPHESUS) shows that Pfizer's selective aldosterone antagonist Planep may be beneficial in improving survival rates during the 30 days of treatment in patients after a heart attack.

6,600 patients participated in the EPHESUS clinical study (full name: Planep Heart Failure Efficacy and Survival Rate Study after Acute Myocardial Infarction). Planep was approved by the United States and the European Union in 2004.

During the 30-day treatment period, patients taking Planep + standard treatment significantly reduced the risk of total death (31%), cardiovascular mortality (32%), and sudden death (37%) compared with standard treatment alone. The results have been published in a related topic in the Journal of the American College of Cardiology (August 2005).

The results of the EPHESUS study were first reported at the American College of Cardiology Annual Meeting in 2003 and published in the New England Journal of Medicine at the same time. The results showed that patients with heart disease can significantly reduce morbidity and mortality after treatment with Planep.

in 2002. Planep has been approved by the State Food and Drug Administration for clinical use. The pure product is white or off-white crystals. Planep has a stronger effect than spironolactone and has extremely low affinity for androgen and progesterone receptors. It has few adverse reactions. It has definite efficacy in the treatment of hypertension, heart failure and myocardial infarction. It has fewer adverse reactions and good tolerance. It is a good alternative drug to spironolactone.

The above is the relevant content about the therapeutic effect!