依普利酮作用及价格

Eplerenone (Planep) is a selective aldosterone receptor antagonist that only acts on mineralocorticoid receptors but not on androgen and progesterone receptors. Eplerenone treats patients with stage 1 and stage 2 hypertension with similar efficacy rates and reductions in systolic and diastolic blood pressure as enalapril. Eplerenone also has a good antihypertensive effect in patients with essential hypertension with low renin levels for whom angiotensin-converting enzyme inhibitors and angiotensin II receptor inhibitors are not effective. It also has a good antihypertensive effect on simple systolic hypertension, and has a good antihypertensive effect on diet-induced obesity-related hypertension. In addition, eplerenone can significantly reduce the ultrafiltration effect of glomeruli and reduce albuminuria in patients with hypertension. This renal protective effect is more obvious for hypertensive patients with diabetes.

Eplerenone (Planep) was approved for clinical use by the State Food and Drug Administration in 2002. It has a stronger antagonizing effect on aldosterone than spironolactone, and has extremely low affinity for androgen and progesterone receptors. It has few adverse reactions. It has definite efficacy in the treatment of hypertension, heart failure and myocardial infarction, has fewer adverse reactions and is well tolerated. It is a good alternative to spironolactone.

At present, eplerenone (Planep) is already on the market in India. The eplerenone on the market in India is produced by Lupine Pharmaceuticals of India. The specification of eplerenone is 50mg*100 tablets, and the price is equivalent to RMB 500. There are two ways for domestic patients to buy Indian eplerenone (Planep). One is to buy it abroad in person, find a hospital doctor to write a prescription, and then take the medicine back to China for treatment. However, this way is time-consuming, costly and not very feasible. The second is to find domestic overseas medical service agencies (such as Medical Companion Travel). They will translate the cases, contact experienced doctors to write prescriptions, and express the drugs to the patients by direct mail from the pharmaceutical factory. They will also guide and answer questions for the patients during the medication. This is currently the most economical and feasible solution.