依普利酮中国上市时间

Eplerenone launch time in China: Currently, Eplerenone is not yet available in China. It is understood that the price of Eplerenone on the market in India is relatively cheap. For detailed drug information of Eplerenone, patients are recommended to consult their medical companions and travel services.

Eplerenone is a selective aldosterone receptor antagonist that only acts on mineralocorticoid receptors but not on androgen and progesterone receptors. Eplerenone treats patients with stage 1 and stage 2 hypertension with similar efficacy rates and reductions in systolic and diastolic blood pressure as enalapril. Eplerenone also has a good antihypertensive effect in patients with essential hypertension with low renin levels for whom angiotensin-converting enzyme inhibitors and angiotensin II receptor inhibitors are not effective.

Eplerenone also has a good antihypertensive effect on simple systolic hypertension, and has a good antihypertensive effect on diet-induced obesity-related hypertension. In addition, eplerenone can significantly reduce the ultrafiltration effect of glomeruli and reduce albuminuria in patients with hypertension. This renal protective effect is more obvious for hypertensive patients with diabetes.

Precautions for the use of Eplerenone: (1) Eplerenone cannot be combined with potassium supplements, potassium-containing salts or contraindicated drugs (potassium-sparing diuretics, strong inhibitors of CYP450 liver enzymes). (2) Non-steroidal anti-inflammatory drugs and lithium can affect the blood concentration of this product and affect its efficacy. (3) Patients with high serum potassium, type 2 diabetes patients with microalbuminuria, patients with high serum creatinine levels, and patients with muscle intoxication clearance <50 mL/min should not take this product. (4) Pregnant women, children, and those with hepatic insufficiency, chronic cardiac insufficiency, and renal insufficiency should use Eplerenone with caution.