依普利酮治好高血压吗

Can high blood pressure be cured? The indications of eplerenone are: congestive heart failure after acute myocardial infarction: eplerenone can improve the quality of life of patients with left ventricular dysfunction (ejection fraction ≤ 40%). Clinical trials have proven that this product can also be used for congestive heart failure after acute myocardial infarction; anti-hypertension: eplerenone can be used alone or in combination with other antihypertensive drugs for the treatment of hypertension.

The trial compared the efficacy and safety of eplerenone and losartan in the treatment of hypertension. Methods 80 patients were selected and randomly divided into eplerenone group and losartan group, 40 cases in each group. Eplerenone tablets 50 mg and Losartan potassium tablets 50 mg were given orally once/d for 12 weeks. Before treatment and after the course of treatment, a number of biochemical indicators, 24-hour ambulatory blood pressure, and adverse reactions were recorded. Compared with before treatment, the blood pressure of the two groups dropped significantly, and the differences were statistically significant.

Comparing the two groups, there was no statistically significant difference in blood pressure reduction between eplerenone and losartan. Comparing the biochemical indicators between the two groups, the difference was not statistically significant. Conclusion Both eplerenone and losartan, 50 mg once/d, can effectively control blood pressure in patients with mild to moderate hypertension, with good safety and compliance.

However, taking eplerenone for treatment will also produce certain side effects or adverse reactions, including: hyperkalemia/hypertriglyceridemia/dizziness/fatigue/hyponatremia/proteinuria/hypercholesterolemia/abdominal pain/increased serum creatinine/cough/angioedema/increased liver enzymes/rash, etc. Therefore, patients must go to the hospital for detailed examination before receiving this drug for treatment, and use the drug strictly according to the doctor's diagnosis and treatment recommendations.

Recommended related hot articles: /newsDetail/79943.html