氢化可的松片（hydrocortisone）详细说明书

(hydrocortisone) detailed instructions

[Drug Name] Hydrocortisone tablets, hydrocortisone

[Indications of Hydrocortisone] It is mainly used for the replacement treatment of adrenal insufficiency and the treatment of congenital adrenal hyperplasia. It can also be used for rheumatoid arthritis, rheumatic fever, gout, bronchial asthma, allergic diseases, and can be used for severe infection and anti-shock treatment.

[Hydrocortisone usage and dosage] Take orally.

1. For the treatment of adrenal insufficiency in adults, the daily dose is 20-30 mg, take 2/3 in the morning and 1/3 after lunch.

2. When there is stress, the dosage should be increased appropriately, up to 80mg per day, taken in divided doses.

3. The therapeutic dose for children is 20 to 25/m^2 per day based on body surface area, divided into 3 times and taken once an hour.

[Adverse reactions of hydrocortisone] The main manifestations are iatrogenic Cushing's syndrome in face and posture, weight gain, lower limb edema, purple lines, prone to bleeding, poor wound healing, acne, menstrual disorders, avascular necrosis of the humeral or femoral head, osteoporosis and fractures (including spinal compression bone fractures). fractures, long bone pathological fractures), muscle weakness, muscle atrophy, hypokalemia syndrome, gastrointestinal irritation (nausea, vomiting), pancreatitis, peptic ulcer or perforation, growth inhibition in children, glaucoma, cataracts, benign increased intracranial pressure syndrome, impaired glucose tolerance and exacerbation of diabetes.

[Precautions for hydrocortisone]

1. Initiation of infection: Under the action of hormones, infections that have been previously controlled can become active. The most common case is the recurrence of tuberculosis infection. The application of hormones in certain infections can reduce tissue damage, reduce exudation, and alleviate the symptoms of infection and poisoning. However, effective antibiotics must be used at the same time, and changes in the condition must be closely observed. After short-term use of this drug, the dose should be quickly reduced and the drug discontinued.

2. Follow-up examination: Those who use glucocorticoids for a long time should regularly check the following items:

(1) Blood glucose, urine glucose or glucose tolerance test, especially for those with diabetes or diabetic tendencies.

(2) Children's growth and development should be monitored regularly.

(3) Eye examination to pay attention to the occurrence of cataracts, glaucoma or eye infections.

(4) Serum electrolytes and fecal occult blood.

(5) Check for high blood pressure and osteoporosis, with special attention to the elderly.

(6) The dosage should be reduced slowly during medication and should not be stopped suddenly.

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