氢化可的松片什么时候吃比较合适？副作用是什么？

Hydrocortisone tablets are short-acting glucocorticoids and are the drug of choice for hormone replacement therapy for adult hypopituitarism. They can regulate hormone levels and relieve patients' fatigue and other related clinical symptoms by regulating corticotropin-releasing hormone and glucocorticoid receptors. At the same time, it has good anti-inflammatory effects, can inhibit the accumulation of inflammatory cells, increase the body's tolerance to harmful stimuli, reduce the damage caused by endotoxins to the body, and enhance the clinical treatment effect. Recently, many people have come to ask, when is the best time to take hydrocortisone tablets? What are the side effects?

Recommended dose of hydrocortisone tablets: oral administration, for the treatment of adrenocortical insufficiency in adults, daily dose of 20-30 mg, take 2/3 in the morning and 1/3 after lunch. In case of stress, the dosage should be increased appropriately, up to 80mg per day, taken in divided doses. The therapeutic dose for children is 20~25mg/㎡ per day based on body surface area, divided into 3 times and taken once every hour.

: Iatrogenic Cushing's syndrome, face and posture, glaucoma, cataracts, prone to bleeding, poor wound healing, weight gain, avascular necrosis of the humeral or femoral head, muscle weakness, muscle atrophy, hypokalemia syndrome, gastrointestinal irritation (nausea, vomiting), lower limb edema , purple striae, pancreatitis, peptic ulcer or perforation, osteoporosis and fractures (including vertebral compression fractures, pathological fractures of long bones), growth inhibition in children, benign intracranial hypertension syndrome, acne, menstrual disorders, impaired glucose tolerance, aggravation of diabetes, etc.

During the period of using hydrocortisone tablets, it is recommended that patients strictly follow the doctor's instructions to take the medication to maximize the effect of hydrocortisone tablets. They must not change the medication time and dosage on their own. You must know that even if you increase the dosage of the drug, there is no way to improve the actual therapeutic effect of the drug. On the contrary, it may cause more adverse reactions, so do not use the drug blindly.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.