港版氢化可的松片有什么副作用？

(Hydocortisone) is an important adrenocortical hormone. It is not only one of the most important immediate anti-inflammatory drugs and immunosuppressants, but also has the characteristics of low dose, long duration and accurate efficacy. It is often used in clinical practice as a replacement therapy for the treatment of adrenal insufficiency and congenital adrenal hyperplasia, and has shown good efficacy. Despite this, when patients actually take hydrocortisone tablets, the drug will still produce some side effects, and the same is true for the Hong Kong version of hydrocortisone tablets. Patients need to pay high attention to this.

The main side effects of the Hong Kong version of hydrocortisone tablets include acne, menstrual disorders, iatrogenic Cushing's syndrome, face and posture, weight gain, lower limb edema, purple striae, pancreatitis, prone to bleeding, poor wound healing, avascular necrosis of the humeral or femoral head, muscle weakness, muscle atrophy, and hypokalemia syndrome. Syndrome, osteoporosis and fractures (including vertebral compression fractures, pathological fractures of long bones), gastrointestinal irritation (nausea, vomiting), peptic ulcer or perforation, growth inhibition in children, glaucoma, cataracts, benign increased intracranial pressure syndrome, impaired glucose tolerance and exacerbation of diabetes.

Hydrocortisone tablets generally have no obvious adverse reactions when physiological dose replacement therapy is used. Adverse reactions mostly occur when applying pharmacological doses of drugs, and are closely related to the course of treatment, dosage, type of medication, usage and route of administration. In actual treatment, it is best to proceed under the guidance of a doctor.

In addition, sudden discontinuation of the drug while taking it can cause glucocorticoid withdrawal syndrome. Sometimes patients experience loss of appetite, nausea, vomiting, dizziness, fainting tendencies, headache, fatigue, abdominal or back pain, low fever, muscle or joint pain, and weakness after stopping the drug. After careful examination, if adrenal insufficiency and relapse of the original disease can be ruled out, glucocorticoid dependence syndrome can be considered.

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