罗氟司特的使用方法是什么？有什么副作用？

Roflumilast, as the world's first PDE-4 inhibitor drug approved for the treatment of chronic obstructive pulmonary disease (COPD), provides a new idea for the treatment of COPD. The drug can selectively inhibit PDE-4, reduce the degradation of cyclic AMP, thereby reducing the release of inflammatory substances, blocking inflammatory signal transmission, thereby inhibiting damage to lung tissue. In addition, the drug and its metabolites can also inhibit the release of superoxide free radicals to antagonize oxidative stress reactions. After research, it was found that it has good efficacy in treating AECOPD, has significant anti-inflammatory effects, and can effectively improve patients' lung function.

Chronic obstructive pulmonary disease (COPD) is a disease characterized by persistent airflow limitation and is related to abnormal inflammatory responses to harmful gases and harmful particles. It has high morbidity and mortality. According to relevant reports, the global incidence rate among people over 40 years old has reached as high as 9% to 10%.

So, how to use roflumilast? What are the side effects?

: The recommended dose for patients with COPD is 500 mcg once daily, with or without food.

: Back pain, flu, dizziness, loss of appetite, weight loss, diarrhea, insomnia, nausea, headache, etc.

Finally, the editor of Medical Companion Travel would like to remind patients who are currently taking roflumilast that there has been a lot of loose news recently saying that if patients feel that the effect of the drug is not good, they can increase the dose of the drug, or that the dose of the drug can be reduced if the side effects are too great during the medication. These are all without scientific basis. Only by following the doctor's instructions can the effect of the drug itself be maximized.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.