能倍乐 思力华噻托溴铵副作用是什么

Chronic bronchitis is a common respiratory disease. Patients suffering from this disease usually need to carry external medicine with them to avoid sudden emergencies. In terms of medication, you may wish to know more about it.

So "a medicine is three parts poisonous". Any medicine taken for a long time will have side effects. So what are the side effects of taking Respimat, Slivar, Tiotropium Bromide? Let’s take a look:

Respimat, Slivar, Tiotropium bromide side effects: 1. Overview In a clinical trial of 906 patients receiving tiotropium bromide for 1 year, the most frequently occurring adverse reaction was dry mouth. Dry mouth occurs in approximately 14% of patients. Dry mouth reactions are usually mild and resolve with continued treatment.

2. Listed below are the reporting rates of this adverse reaction, which are derived from clinical trials (according to WHO organ system classification) of patients treated with Respimat, Slava, Tiotropium for 1 year. Frequency of adverse reactions Systemic allergic reactions: Rare (i.e., >0.1%, <1%) Gastrointestinal system disorders: dry mouth Very common (i.e., >10%) Constipation Common (i.e., >1%, <10%) Heart rate and rhythm disorders: Tachycardia Uncommon (i.e., >0.1%, <1%) Palpitations Uncommon (i.e., >0.1%, <1%) Immune system disorders: Candida infection Common (i.e., >1%, <10%) Respiratory disorders: Sinusitis Common (i.e., >1%, <10%) Pharyngitis Common (i.e., >1%, <10%) Urinary disorders: Dysuria Uncommon (i.e., >0.1%, <1%) Urinary retention Rare (i.e., >0.1%, <1%) All adverse events listed as common refer to a reported frequency of greater than 1% to 2% compared to placebo. Postmarketing Experience: Spontaneous adverse reaction reports of nausea, hoarseness, and dizziness have been received.

3. Regarding individual serious and/or frequently occurring adverse reactions. The most common adverse reaction of anticholinergic treatment in COPD patients is dry mouth. Dry mouth symptoms are mild in most cases. In general, dry mouth occurs between the 3rd and 5th week after treatment. Dry mouth symptoms usually resolve as patients continue treatment. In a 1-year clinical trial of 906 patients, 3 patients (accounting for 0.3% of the total number of patients treated) terminated the trial due to adverse reactions of dry mouth. In the 1-year clinical trial of the drug, constipation and urinary retention were the serious and persistent adverse reactions reported in individual cases. Urinary retention is only seen in older men with predisposing factors (eg, enlarged prostate). Ventricular tachycardia and atrial fibrillation have occurred in individual cases after the use of tiotropium bromide, usually in susceptible patients. As with all inhaled treatments, tiotropium may cause bronchospasm due to inhaled irritation. Spontaneous adverse reactions Reported allergic reactions include angioedema, rash, urticaria, and pruritus.

4. Pharmacological classification of adverse reactions There are many organ systems and functions that are controlled by the parasympathetic nervous system and are therefore susceptible to the effects of anticholinergic agents. Adverse reactions that may be associated with systemic anticholinergic effects include dry mouth, dry throat, increased heart rate, blurred vision, glaucoma, dysuria, urinary retention, and constipation. In addition, upper respiratory tract irritation may occur in patients who inhale tiotropium bromide. The incidence of dry mouth and constipation increases with age.

If these reactions occur after taking it, you don’t need to worry if they are mild symptoms. They will subside on their own over time. If they are serious side effects, it is recommended that you seek medical treatment.

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